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  • Title: A novel poly (glycine) biosensor towards the detection of indigo carmine: A voltammetric study.
    Author: Manjunatha JGG.
    Journal: J Food Drug Anal; 2018 Jan; 26(1):292-299. PubMed ID: 29389566.
    Abstract:
    The electrochemical behavior of indigo carmine (IC) at poly (glycine) modified carbon paste electrode (PGMCPE) was investigated by cyclic and differential pulse voltammetry. The oxidation peak of IC was observed in phosphate buffer of pH 6.5. The influence of different pH, scan rate, and concentration were analyzed. The probable reaction mechanism involved in the oxidation of IC was also proposed. Results showed that PGMCPE a remarkable electrocatalytic activity for the oxidation of IC under optimal conditions. The electrocatalytic response of the sensor was proportional to the IC concentration in the range of (2 × 10-6-1 × 10-5 M) and (1.5 × 10-5-6 × 10-5 M) with a limit of detection 11 × 10-8 M and limit of quantification 3.6 × 10-7 M. The modified electrode demonstrated many advantages such as simple preparation, high sensitivity, low detection of limit, excellent catalytic activity, short response time, and remarkable antifouling property toward IC and its oxidation product.
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