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  • Title: [Determination of serum and saliva concentrations of clindamycin (Dalacin C) and amoxicillin (Clamoxyl)].
    Author: Fricker U, Osborn JF, Wüst J.
    Journal: SSO Schweiz Monatsschr Zahnheilkd; 1979 Aug; 89(8):738-47. PubMed ID: 293922.
    Abstract:
    The antibiotic therapy of oral infections requires bactericidal concentrations in the oral environment over sufficient time. Comparable determination of antibiotica concentration in the saliva of 8 human volunteers were made after oral application of Amoxycillin and Clindamycin. Only Clindamycin showed inhibitory concentrations.--When pharmacokinetic characteristics and the present status of resistance were considered, Clindamycin is viewed as an antibiotic of choice for oral infections.
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