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  • Title: [A Case of Curatively Resected Ascending Colon Cancer with Ovarian Metastasis and Peritoneal Dissemination after Chemotherapy].
    Author: Mochizuki Y, Karasawa H, Shimodaira H, Ohnuma S, Watanabe K, Maeda S, Nagao M, Aoki T, Kudo K, Tanaka N, Musha H, Motoi F, Kamei T, Naitoh T, Unno M.
    Journal: Gan To Kagaku Ryoho; 2017 Nov; 44(12):1711-1713. PubMed ID: 29394751.
    Abstract:
    A52 -year-old woman was diagnosed with ascending colon cancer with ovarian metastasis and peritoneal dissemination. Since the patient did not have symptoms with intestinal obstruction, mFOLFOX6 plus bevacizumab(Bmab)was performed for 12 cycles. After chemotherapy, the tumors of ascending colon and ovary were significantly shrunken and novel distant metastasis was not observed by CT scans. Therefore, the tumors were considered to be resectable and curative resection was performed. In the surgical findings, the peritoneal disseminations were localized, and right colectomy, bilateral oophorectomy and extirpation of the peritoneal disseminations were performed. R0 resection was pathologically achieved and adjuvant chemotherapy with UFT/UZEL was administrated for 6 months. The patient is alive without recurrence for 1 year. Since right sided colon cancer is less likely to have obstruction, upfront chemotherapy can be a strategy for locally advanced right sided colon cancer with distant metastasis.
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