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  • Title: Comparative in vitro activity of seven quinolones against 100 clinical isolates of Clostridium difficile.
    Author: Delmee M, Avesani V.
    Journal: Antimicrob Agents Chemother; 1986 Feb; 29(2):374-5. PubMed ID: 2940968.
    Abstract:
    The in vitro activity of seven quinolone derivatives against 100 clinical isolates of Clostridium difficile was determined. CI934 was the most active, inhibiting 90% of the strains at 4 micrograms/ml and 100% at 8 micrograms/ml. Ofloxacin and ciprofloxacin had moderate activity (16 and 32 micrograms/ml) whereas enoxacin, pefloxacin, norfloxacin, and nalidixic acid had poor activity (128 micrograms/ml).
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