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  • Title: Lactobacillus crispatus represses vaginolysin expression by BV associated Gardnerella vaginalis and reduces cell cytotoxicity.
    Author: Castro J, Martins AP, Rodrigues ME, Cerca N.
    Journal: Anaerobe; 2018 Apr; 50():60-63. PubMed ID: 29427630.
    Abstract:
    Using a chemically-defined medium simulating genital tract secretions, we have shown that pre-adhering Lactobacillus crispatus to Hela epithelial cells reduced cytotoxicity caused by Gardnerella vaginalis. This effect was associated to the expression of vaginolysin and was specific to L. crispatus interference, as other vaginal facultative anaerobes had no protective effect.
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