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  • Title: Synthesis of photothermal nanocomposites and their application to antibacterial assays.
    Author: Yang N, Wang C, Wang X, Li L.
    Journal: Nanotechnology; 2018 Apr 27; 29(17):175601. PubMed ID: 29451132.
    Abstract:
    In this work, we report a novel gold nanorod (AuNR)-based nanocomposite that shows strong binding to bacterium and high antibacterial efficiency. The AuNRs were used as a photothermal material to transform near-infrared radiation (NIR) into heat. We selected poly (acrylic acid) to modify the surface of the AuNRs based on a simple self-assembly method. After conjugation of the bacterium-binding molecule vancomycin, the nanocomposites were capable of efficiently gathering on the cell walls of bacteria. The nanocomposites exhibited a high bacterial inhibition capability owing to NIR-induced heat generation in situ. Therefore, the prepared photothermal nanocomposites show great potential for use in antibacterial assays.
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