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  • Title: [Inhibitory effect of various hydrazine derivatives on the activity of L-phenylalanine ammonia-lyase from Rhodotorula glutinis].
    Author: Munier RL, Bompeix G, Saindrenan P.
    Journal: C R Seances Soc Biol Fil; 1986; 180(3):302-8. PubMed ID: 2946374.
    Abstract:
    The inhibitory activities of hydrazinoacetic acid (HAA), 2-hydrazinoethanol (HE) and ethyl hydrazino-acetate (EHA) are characterized and compared with those of L-or D-alpha-hydrazino-beta-phenylpropionic acid (L-or D-HPPA), 2-phenylethylhydrazine (PEH), hydrazine (H), alpha, beta-dihydrocinnamic acid (DHCA) and D-phenylalanine (D-Phe). Inhibitors can be arranged in order of increasing activity: HE less than EHA less than H less than D-Phe less than HAA less than D-HPPA less than DHCA less than PEH less than L-HPPA. Relations between activity and structure of inhibitors are discussed.
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