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Title: Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis. Author: Leutou AS, Yang I, Le TC, Hahn D, Lim KM, Nam SJ, Fenical W. Journal: J Antibiot (Tokyo); 2018 Jun; 71(6):609-612. PubMed ID: 29467379. Abstract: A new 14-membered macrolactam natural product, fluvirucin B6 (1), was isolated from a marine-derived actinomycete, Nocardiopsis sp. CNQ-115, via HPLC-UV guided isolation. The chemical structure of 1 was elucidated by 1D and 2D NMR spectroscopic data analysis. Compound 1 showed a weak activity against Gram-positive bacteria, whereas it was inactive against Gram-negative bacteria.[Abstract] [Full Text] [Related] [New Search]