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  • Title: Do celiac disease and non-celiac gluten sensitivity have the same effects on reproductive disorders?
    Author: Pieczyńska J.
    Journal: Nutrition; 2018 Apr; 48():18-23. PubMed ID: 29469015.
    Abstract:
    OBJECTIVES: The wide spectrum of clinical symptoms of celiac disease (CD) is partly due to the malnourished state caused by the malabsorption of micro- and macronutrients. It has been suggested that fertility problems and obstetric complications may be a consequence of the endocrine disorders caused by selective nutrient deficiencies. The same selective nutrient deficiencies as in CD could be a reason for fertility problems in non-celiac gluten sensitivity (NCGS). The aim of this study was to investigate the effect of nutrient deficiencies in CD and NCGS on fertility problems. METHOD: A literature review of fertility problems in men and women and nutrient deficiencies associated with CD and NCGS, was performed up to May 2017. RESULTS: The same selective nutrient deficiencies (folate, iron, vitamin B12, and vitamin D) in CD and NCGS could be a reason for fertility problems. CONCLUSIONS: CD is postulated to be considered in the preconceptional screening of patients with reproductive disorders, but for non-celiac gluten sensitivity, the effect on fertility is not yet proven.
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