These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Beta-endorphin and beta-lipotrophin in human ovary.
    Author: Laatikainen T, Salminen K, Wahlström T.
    Journal: Neuropeptides; 1986 Oct; 8(3):251-8. PubMed ID: 2946978.
    Abstract:
    The presence of beta-endorphin (beta-E) and beta-lipotrophin (beta-LPH) in human ovary was studied by liquid chromatography and radioimmunoassay, and by immunoperoxidase staining. The mean concentrations (+/- S.E., N=8) of beta-E and beta-LPH in follicular fluid samples collected during the late follicular phase of normal cycles were 1.9 +/- 0.4 pmol/l and 2.9 +/- 0.8 pmol/l, respectively. After hyperstimulation with clomiphene and gonadotropin for in vitro fertilization, the mean concentrations of beta-E and beta-LPH in follicular fluid did not increase significantly, being 3.2 +/- 0.6 and 4.1 +/- 1.0 pmol/l, respectively (N=13). beta-E or beta-LPH were not found in three corpora lutea analysed. Immunohistochemical staining of ovarian tissue did not reveal any beta-E immunoreactivity. Thus the origin of beta-E and beta-LPH in the follicular fluid remained unclear. In 7 women, blood samples were collected from the peripheral and ovarian veins at laparotomy. No significant concentration excess of beta-E or beta-LPH was found in the ovarian venous plasma, suggesting that human ovaries do not secrete significant amounts of beta-E or beta-LPH into the peripheral circulation. It seems that the role of endorphins in the human ovary is less significant than previously proposed for sheep, rat or mouse ovary.
    [Abstract] [Full Text] [Related] [New Search]