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  • Title: Methodical aspects of the experimental chemotherapy of viral infections.
    Author: Galabov AS, Galegov GA.
    Journal: Acta Virol; 1978 Jul; 22(4):343-51. PubMed ID: 29480.
    Abstract:
    An analysis of the methods of testing the antiviral activity in vitro (in cell cultures) and in vivo (in experimental virus infections) is presented. The necessity of applying two-stage screening in vitro is emphasized. The chemotherapeutic viral models is in vitro testing as well as the principles of modelling of experimental viral infections are examined. Criteria for stage-by-stage assessment of the antiviral activity of the substances tested are formulated.
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