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  • Title: The theoretical implications of chlorpromazine as a sensory integrative theory.
    Author: Saffir JS.
    Journal: Am J Occup Ther; 1978 Aug; 32(7):460-6. PubMed ID: 29481.
    Abstract:
    In order to evaluate the influence of antipsychotic drugs used in the treatment of schizophrenia on therapy based on sensory integrative theory, this study, developed through library research, explores the theoretical bases for these two modes of treatment. Studies of chlorpromazine, a prototypical antipsychotic drug, show that its local action on the neurotransmitters of the brain may explain in theory its therapeutic efficacy. By citing evidence of sensory processing deficits in schizophrenic patients, a theoretical basis for the use of a sensory integrative approach to therapy is established. A comparison of these theories leads to the conclusion that a sensory integrative approach can serve as an important reinforcer of the therapeutic actions of chlorpromazine. Implications for treatment and research are considered.
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