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  • Title: Hematoporphyrin derivative (Photofrin II) photosensitization of isolated mitochondria: impairment of anion translocation.
    Author: Atlante A, Moreno G, Passarella S, Salet C.
    Journal: Biochem Biophys Res Commun; 1986 Dec 15; 141(2):584-90. PubMed ID: 2948508.
    Abstract:
    Isolated mitochondria have been incubated in the presence of 6 micrograms/ml hematoporphyrin derivative (Photofrin II), and irradiated at lambda = 365 nm. After 2 min irradiation (30 W/m2), a congruent to 50% inhibition of citric cycle intermediates transport is observed with a rather similar photosensitivity for the succinate, citrate or oxaloacetate carriers.
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