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  • Title: Reversal by indomethacin of renal effects of dopamine in subjects with normal renal function.
    Author: Yeyati NL, Altenberg GA, Rainoldi FA, Greco J.
    Journal: Acta Physiol Pharmacol Latinoam; 1986; 36(2):127-33. PubMed ID: 2950721.
    Abstract:
    In five subjects with normal renal function, intravenous dopamine, at a rate of 6 ug/kg/min, produces a renal vasodilation, increase in Na excretion and reduction in urinary osmolality, without modification in glomerular filtration rate. These effects were reversed by intravenous indomethacin (2 mg/kg), suggesting that the renal effects of dopamine might depend on normal prostaglandins production.
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