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  • Title: [Myocardiopathies of Friedreich's disease].
    Author: Klein JM, Assyag P, du Cailar G, Koenig A, Chauvin M, Brechenmacher C.
    Journal: Ann Cardiol Angeiol (Paris); 1987 Jan; 36(1):27-30. PubMed ID: 2950821.
    Abstract:
    Cardiac involvement in Friedreich's disease is classically a hypertrophic myocardiopathy, concentric or assymmetrical with or without dilatation. It has nothing specific in comparison to other myocardiopathies. Nevertheless, forms with a dilated myocardiopathy are also possible, but much more unfrequent. A propos of three cases, we have studied the different aspects of myocardiopathies in Friedreich's ataxia. The problem raised by the case of an hypertrophic myocardiopathy evolving toward a dilated form, unusual element of this pathology, is presented. The therapeutic potential of hypertrophic myocardiopathies is classically represented either by beta-blockers or by the more recent slow calcium inhibitors.
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