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  • Title: Trimethoprim associated fixed drug eruption.
    Author: Hughes BR, Holt PJ, Marks R.
    Journal: Br J Dermatol; 1987 Feb; 116(2):241-2. PubMed ID: 2950916.
    Abstract:
    We report two cases of fixed drug eruption due to trimethoprim. Fixed drug eruption is a distinct entity characterized by the development of circular erythematous skin lesions which over a period of time become violaceous and leave an area of hyperpigmentation. Mucous membranes also may be affected. With re-administration of the drug the lesions recur in the same area but may extend to further new areas with each challenge.
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