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  • Title: Association of serum procalcitonin level with in-stent restenosis in patients undergoing bare-metal stent implantation.
    Author: Ornek E, Cetin M, Kiziltunc E, Kurtul A, Gok M, Kundi H.
    Journal: Biomark Med; 2018 May; 12(5):455-463. PubMed ID: 29517279.
    Abstract:
    AIM: Procalcitonin (PCT) is an inflammatory marker and elevated PCT levels are associated with cardiovascular events. We assessed whether PCT level is an independent predictor of bare-metal stent (BMS) in-stent restenosis (ISR). PATIENTS & METHODS: We evaluated 240 patients undergoing BMS implantation. Serum PCT levels were measured before procedure. Patients were classified as ISR(-) group (n = 120) and ISR(+) group (n = 120). RESULTS: Serum PCT levels were higher in the ISR (+) group (p < 0.001). At multivariate analysis, PCT (odds ratio [OR] 1.561; p = 0.012), stent length (OR: 1.089), stent diameter (OR: 0.141) and uric acid (OR: 1.465) were independent predictors of ISR. CONCLUSION: Serum PCT is independently associated with ISR and increased PCT levels may provide useful information for the risk of BMS-ISR.
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