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  • Title: Quantitative scanning of osteogenic sarcoma with nitrogen-13-labeled L-glutamate.
    Author: Gelbard AS, Benua RS, Laughlin JS, Rosen G, Reiman RE, McDonald JM.
    Journal: J Nucl Med; 1979 Jul; 20(7):782-4. PubMed ID: 295364.
    Abstract:
    N-13 L-glutamate was used to image an osteogenic sarcoma in a 9-year-old patient. Serial quantitative measurements of the amount of N-13 taken up by the primary tumor showed a decrease of 40% after 10 wk of chemotherapy. Blood-clearance data obtained from normal subjects indicate that more than 90% of the N-13 activity had left the blood before scanning of the tumor was begun. It appears that the N-13 label concentrated in the soft-tissue portion of this osteogenic sarcoma, whereas Tc-99m diphosphonate uptake was greatest in the regions where calcification was occurring.
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