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  • Title: [Significance of Fc receptors for IgG].
    Author: Hückel C, Brock J.
    Journal: Allerg Immunol (Leipz); 1987; 33(1):15-20. PubMed ID: 2954442.
    Abstract:
    Fc gamma R are glycoproteins or phospholipoproteins respectively. Their molecular weight depends on type and origin of the Fc gamma R-coated cell and was determined between 40 and 115 KD. Fc gamma R can be estimated by means of rosetting assay or binding experiments with isotopic or fluorescein labeled immune complexes or aggregated IgG respectively. Depending on the cell type Fc gamma R are involved in different reactions after respective binding of their ligands. A lot of results are described in the literature, indicating that Fc gamma R bearing T lymphocytes are suppressor cells in the humoral immune response, but generally accepted data about the involvement of Fc gamma R in this suppression do not exist. Some models are represented in this paper.
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