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  • Title: Triterpenoid saponins from Scabiosa stellata collected in North-eastern Algeria.
    Author: Lehbili M, Alabdul Magid A, Kabouche A, Voutquenne-Nazabadioko L, Morjani H, Harakat D, Kabouche Z.
    Journal: Phytochemistry; 2018 Jun; 150():40-49. PubMed ID: 29547709.
    Abstract:
    Eight undescribed triterpenoid saponins, scabiostellatosides A-H, together with three known compounds were isolated from the whole plant of Scabiosa stellata L. Their structures were established by spectroscopic analyses (1D, 2D-NMR and HRESIMS) and chemical methods. Scabiostellatosides A-H were evaluated for their cytotoxicity against human fibrosarcoma cell line (HT1080). Scabiostellatoside F, a heptasaccharide derivative of oleanolic acid, exhibited moderate cytotoxicity against HT1080 cell line with IC50 value of 12.0 μM.
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