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  • Title: Concurrent Acute Myelofibrosis and Acute Lymphoblastic Leukemia in Childhood: Case Report and Review of the Literature.
    Author: Friesenbichler W, Schumich A, Simonitsch-Klupp I, Panzer-Grümayer R, Haas O, Mann G, Dworzak M.
    Journal: J Pediatr Hematol Oncol; 2018 Apr; 40(3):235-237. PubMed ID: 29557917.
    Abstract:
    Myelofibrosis is associated with a wide variety of neoplastic and non-neoplastic bone marrow diseases, predominately myeloproliferative neoplasms and acute myeloid leukemia. The following case documents an unusual patient presenting with pancytopenia and acute myelofibrosis accompanied by precursor B-cell acute lymphoblastic leukemia. This very rare clinical presentation raises questions concerning the relationship between concurrent occurrence of acute myelofibrosis and acute lymphoblastic leukemia.
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