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  • Title: [Contact allergy to the preservative bronopol].
    Author: Frosch PJ, Weickel R.
    Journal: Hautarzt; 1987 May; 38(5):267-70. PubMed ID: 2956218.
    Abstract:
    Six cases of contact allergy to bronopol are described (5 females, 1 male; mean age, 60.8 years). Four patients suffered from stasis dermatitis of the lower leg. The cause of sensitization has been traced to bronopol-containing ointments in 5 of 6 cases. For patch testing 0.25% bronopol in petrolatum is recommended. One-third of the patients were also sensitized to formaldehyde, which is a degradation product of bronopol.
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