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  • Title: Serotonin-induced head shaking behavior in rats does not involve receptors located in the frontal cortex.
    Author: Lucki I, Minugh-Purvis N.
    Journal: Brain Res; 1987 Sep 15; 420(2):403-6. PubMed ID: 2960422.
    Abstract:
    Serotonin-induced head shaking behavior, a response associated with 5-HT2 receptors, was examined in rats with lesions of the frontal cortex because of the high density of 5-HT2 receptors in this area. Head shaking behavior caused by the serotonin precursor, 5-hydroxy-L-tryptophan, or by the serotonergic agonist, quipazine, was unchanged following the complete ablation of the frontal cortex. Although 5-HT2 receptors are associated with the head shake response, this behavior is probably not related to serotonin receptors located in the frontal cortex.
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