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  • Title: [Transplantation strategy in type 1 diabetic patients].
    Author: Buron F, Badet L, Morelon E.
    Journal: Nephrol Ther; 2018 Apr; 14 Suppl 1():S23-S30. PubMed ID: 29606260.
    Abstract:
    Beta cell replacement by pancreas or Langerhans islets transplantation is the only way to restore glucose homeostasis in type 1 diabetic patients. The counterpart is the need for long-term immunosuppression. These transplantations are therefore mainly indicated for patients candidates for kidney transplantation and for patients with poor quality of life due to unstable diabetes with life-threatening hypoglycemic events. Both beta cell replacement techniques have different benefits and risks and should be adapted to each type 1 diabetic patient. The transplant strategy must be personalized according to parameters assessed in the pre-transplant period, validated by a multidisciplinary team and reassessed regularly until transplantation.
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