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Title: Comparison of the ultrasound-guided tru-cut biopsy with postoperative histopathology results in patients with breast mass. Author: Günes ME. Journal: Ann Ital Chir; 2018; 89():30-35. PubMed ID: 29629888. Abstract: AIM: We aimed to compare the tru-cut biopsy and postoperative pathology results of breast lesions with suspicion of malignancy. Furthermore we aimed to determine the efficacy, specificity and sensitivity of the tru-cut biopsy. METHODOLOGY: 140 patients who were operated due to breast mass following tru-cut biopsy were retrospectively evaluated. Patients' demographic characteristics, imaging findings, biopsy and histopathology results were compared. RESULTS: The mean age of 140 patients was 51.3 (Ranged: 17-83 ages). Malignancy was statistically more common in patients older than 45 years old. According to tru-cut biopsy results 103 (73.5%) lesions were malign, 32 (23%) benign, and 5 (3,5%) suspicious. Histopathological evaluation established 113 (% 80.7) malign and 27 (19,3%) benign lesions. Tru-cut biopsy had a sensitivity, specifity, positive predictive value, negative predictive value and diagnostic accuracy of 93.5%, 95.4%, 99%, 75% and 80%, respectively in this study. CONCLUSIONS: Our findings have confirmed that tru-cut biopsy is an accurate, reliable and as effective as open surgery for breast cancer diagnosis. The higher success rates may achieve by accordance of triple assessment which includes clinical, radiological and pathological evaluation with tru-cut biopsy. KEY WORDS: Breast cancer, Core needle biopsy, Preoperative evaluation, Tru-cut biops. Scopo dello studio è di confrontare i referti ago bioptici di lesioni mammarie sospette di malignità ed i risultati anatomo-patologici postoperatori, e dunque di determinare efficacia, specificità e sensibilità della metodica. La casistica studiata retrospettivamente si riferisce a 140 pazienti sottoposte ad intervento per tumefazione mammaria precedentemente studiate con ago-niopsia, mettendo a confronto caratteristiche demografiche, referti dell’maging, referti bioptici e risultati isto-patologici. L’età media delle pazienti era di 51,3 anni (tra 17 e 83). Le neoplasie sono risualtate statisticamente più frequenti nelle donne superiori ai 45 anni. Dai risultati bioptici 103 referti indicavano malignità (73,5%), 32 (23%) benignità, e 5 (3,5%) sospetti. I riscontri istopatologici deinitivi hanno accertato 113 casi di malignità (80,7%) e 27 casi di benignità (19,3%) . La tecnica dell’ago-biopsia ha dimostrato sensibilità, specificità, valore predittivo positivo e negativo ed accuratezza diagnostica rispettivamente del 93.5%, 95.4%, 99%, 75% e 80%. Da questi risultati si conferma che la ago-biopsia è accurata, affidabile e di effetto paragonabile al prelievo chirurgico per la diagnosi di cancro della mammella. Il maggior successo può ottenersi con la associazione di un triplice approccio clinico, radiologico ed istopatologico su biopsia tru-cut.[Abstract] [Full Text] [Related] [New Search]