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Title: [Routine semen parameters and sperm morphological index of infertile males with partial globozoospermia]. Author: Li T, LIu W, Yang SJ, Zhang C, Xie N, Li SJ, Gao X. Journal: Zhonghua Nan Ke Xue; 2017 Jan; 23(1):57-60. PubMed ID: 29658238. Abstract: OBJECTIVE: To investigate the routine semen parameters and sperm morphological indexes of the patients with partial globozoospermia (PGZ). METHODS: We included in this study 100 infertile males with PGZ and another 180 non-PGZ infertile men as controls. According to the proportion of round-headed sperm (RHS) in the semen, we classified the PGZ males into five subgroups: 25%-40%, 41%-55%, 56%-70%, 71%-85%, and 86%-99% RHS. We obtained sperm concentration, total sperm motility, the percentage of progressively motile sperm, teratozoospermia index (TZI), and sperm deformity index (SDI) from the subjects and compared them among different groups. RESULTS: Statistically significant differences were found between the PGZ patients and non-PGZ controls in total sperm motility ([35.76±24.88]% vs [62.03±10.20]%, P<0.01), the percentage of progressively motile sperm ([26.11±20.39]% vs [45.62±6.87]%, P<0.01), the percentage of morphologically normal sperm ([1.45±1.45]% vs [5.98±2.21]%, P<0.01), and SDI (1.33±0.11 vs 1.27±0.57, P<0.01), but not in age ([29.82±4.90] vs [30.33±3.59 ] yr, P>0.05), sperm concentration ([46.01±40.38] vs [54.00±25.15] ×106/ml, P>0.05), or TZI (1.35±0.11 vs 1.34±0.54, P>0.05). There were also significant differences among the five PGZ subgroups in total sperm motility, progressive sperm motility, normal sperm morphology, TZI, and SDI (P<0.01), but not in age or sperm concentration (P>0.05). Morphologically, the sperm head changed from heterogeneous to homogeneous with the increased proportion of round-headed sperm. CONCLUSIONS: Different proportions of round-headed sperm are closely related to routine semen parameters and sperm morphological index in PGZ patients, which can help clinicians choose the proper assisted reproductive technology and predict the rate of fertilization for infertile males. 目的: 分析部分型圆头精子症患者精液常规参数及精子形态。方法: 选取 2013年1月至2016年5月100例部分型圆头精子症患者作为病例组,对照组为非圆 头精子症的不育患者180例。根据精液中圆头精子所占比例不同将病例组分成5组:1组(25%~40%)、2组(41%~55%)、3组(56%~70%)、4组(71%~85%)、5组 (86%~99%),根据WHO《人类精液检查与处理实验室手册》第5版标准对其进行精液常规分析,包括精子浓度、活动率、前向运动精子百分率,及对不同畸形精子进行 计数并计算畸形精子指数(TZI)及精子畸形指数(SDI)。结果: 病例组与对照组的精子活动率[(35.76±24.88)% vs (62.03±10.20)%]、前向运动精子 百分率[(26.11±20.39)% vs (45.62±6.87)%]、正常形态精子百分率[(1.45±1.45)% vs (5.98±2.21)%]和SDI(1.33±0.11 vs 1.27±0.57)相比差异均有统计学意义(P均<0.01),两组年龄[(29.82±4.90)岁 vs (30.33±3.59)岁]、精子浓度[(46.01±40.38) ×10⁶/mlvs (54.00±25.15)×106/ml]和TZI(1.35±0.11 vs 1.34±0.54)比较差异均无统计学意义(P均>0.05);病例组各组精 子活动率、前向运动精子百分率、正常形态精子百分率、TZI和SDI均有统计学差异(P均<0.01),而年龄和精子浓度均无统计学差异(P均>0.05)。随着圆头 精子比例的升高,精子头部形态由异质性偏向于均一性。结论: 精液中不同比例的圆头精子与精液常规参数和形态学指标密切相关,可对不育患者辅助生殖技术的选 择和受精率的预测起一定的提示作用。.[Abstract] [Full Text] [Related] [New Search]