These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Structurally diverse diterpenoids from Trigonostemon howii.
    Author: Liu YP, Wen Q, Hu S, Ma YL, Jiang ZH, Tang JY, Fu YH.
    Journal: Nat Prod Res; 2019 Apr; 33(8):1169-1174. PubMed ID: 29658332.
    Abstract:
    Phytochemical investigation on the stems and leaves of Trigonostemon howii resulted in the isolation of a new abietane diterpenoid, trigohowimine A (1), along with seven known structurally diverse diterpenoids (2-8). The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparison with data reported in the literature. New compound 1 was evaluated for its cytotoxicities against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480. Compound 1 showed significant inhibitory effects against various human cancer cell lines with IC50 values ranging from 0.82 to 8.53 μM.
    [Abstract] [Full Text] [Related] [New Search]