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  • Title: Ribosomal DNA inheritance and recombination in Neurospora crassa.
    Author: Russell PJ, Petersen RC, Wagner S.
    Journal: Mol Gen Genet; 1988 Mar; 211(3):541-4. PubMed ID: 2966889.
    Abstract:
    The genetic segregation of ribosomal DNA (rDNA) in Neurospora crassa was analyzed by exploiting restriction fragment length polymorphisms in the nontranscribed spacer (NTS) sequences of nine laboratory wild-type strains and wild-collected strains. In an analysis of random spore progeny from seven crosses, and of ordered tetrads from two of those crosses the rDNA was shown to be inherited in a simple, stable Mendelian fashion, exhibiting an approximately 1:1 ratio of the two parental rDNA types. No meiotic recombinants were detected among the progeny, indicating that non-sister-chromatid crossing over is highly suppressed in the rDNA region. The basis for this suppression of meiotic recombination is not known.
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