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  • Title: Doppler assessment of uterine blood flow changes in patients with fibroids receiving the gonadotropin-releasing hormone agonist Buserelin.
    Author: Matta WH, Stabile I, Shaw RW, Campbell S.
    Journal: Fertil Steril; 1988 Jun; 49(6):1083-5. PubMed ID: 2967195.
    Abstract:
    Uterine arterial blood FVWs were studied by doppler ultrasound in eight patients with large uterine fibroids who were treated with the GnRH agonist Buserelin intranasally for 4 months. At the end of treatment, reductions in the uterine and discrete fibroid volumes were associated with significant increases in the mean RI values for the uterine (P less than 0.01) and fibroid (P less than 0.001) vasculature, thus indicating reduction in blood flow.
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