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  • Title: [Paradoxical hyperglucagonemia after oral administration of glucose in diabetic dogs. Impact of the cholinergic nervous system].
    Author: Hillaire-Buys D, Ribes G, Gross R, Loubatières-Mariani MM.
    Journal: C R Seances Soc Biol Fil; 1987; 181(6):677-82. PubMed ID: 2970286.
    Abstract:
    Alloxan diabetic dogs with insulin deficiency showed a transient but significant rise in glucagon levels after oral glucose load (1 g/kg). Pretreatment with atropine sulfate (0.2 mg/kg intravenously) totally suppressed this increase. So, the transient paradoxical rise of glucagon level observed in diabetic dogs after glucose intake is under cholinergic control.
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