These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Synthesis, characterization and SAR of novel Bezimidazole derivatives as Nematicidal agents.
    Author: Asghar N, Akhtar S, Naeem S, Ahmed A, Faizy S, Arif M, Saify ZS.
    Journal: Pak J Pharm Sci; 2018 May; 31(3):827-833. PubMed ID: 29716862.
    Abstract:
    Six novel analogues were prepared by reacting benzimidazole molecules (BM and CMB) propiophenone and benzoyl chlorides respectively. The structures of newly synthesized compounds were determined with the help of spectroscopic techniques. The compounds were subjected to in-vitro screening for their activity against nematodes. It was observed that the benzimidazole (BM) derivatives possessed more nematicidal activity as compared to that of cyanomethyl-benzimidazole (CMB) for Meloidogyne incognita. Among them, the propiophenone substituted benzimidazole derivative B3 was found to be the most active compound and can be further studied as lead molecule for development of anthelmintic drugs.
    [Abstract] [Full Text] [Related] [New Search]