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  • Title: [Inhibiting effect of a chalone-containing extract of calf pancreatic tissue on the proliferative activity of normal and tumorous pancreatic cells in vitro and in vivo].
    Author: Mkrtchian LN, Khachaturova TS, Shukurian SG, Aleksanian KA, Melik-Shakhnazarian RB.
    Journal: Eksp Onkol; 1988; 10(4):63-6. PubMed ID: 2972536.
    Abstract:
    The pancreatic chalone has been studied for its effect on the proliferative activity and morphology of normal and tumour cells of the pancreas. These findings in experiments in vitro were confirmed by the data of the in vivo experiments. The results show that pancreatic chalone inhibits cell proliferation, decreases mitotic index and causes morphologic changes in cultivated pancreatic cells.
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