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  • Title: [Pemphigus herpetiformis following D-penicillamine in a patient with HLA B8].
    Author: Weltfriend S, Ingber A, David M, Sandbank M.
    Journal: Hautarzt; 1988 Sep; 39(9):587-8. PubMed ID: 2972666.
    Abstract:
    A 57-year-old patient with rheumatoid arthritis, who was being treated with D-penicillamine, developed a bullous eruption 2 months after the onset of treatment. On the basis of the clinical, histological and immunofluorescent findings, the diagnosis of herpetiform pemphigus was made. The eruptions disappeared within 2 weeks after the discontinuation of D-penicillamine treatment. During the 16-month follow-up period there was no recurrence. It is noteworthy that a patch test with potassium iodide was positive and that testing for HLA antigens revealed HLA B8, A1, A2, and BW39.
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