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  • Title: Dehydroepiandrosterone sulphate and dehydroepiandrosterone in serum: differences related to age and sex.
    Author: Carlström K, Brody S, Lunell NO, Lagrelius A, Möllerström G, Pousette A, Rannevik G, Stege R, von Schoultz B.
    Journal: Maturitas; 1988 Dec; 10(4):297-306. PubMed ID: 2976116.
    Abstract:
    Serum concentrations of dehydroepiandrosterone sulphate (DHAS) were determined in 590 healthy women aged 20-87 yr. Simultaneous assays of dehydroepiandrosterone (DHA) were performed in 417 of the women. DHA and DHAS levels correlated negatively with age while the DHA/DHAS ratio proved to be unrelated to age. When values for 60 healthy men in the age range 20-84 yr were compared with those obtained in 60 randomly-selected healthy women who were exactly age-matched, the DHAS levels were found to be significantly lower and the DHA/DHAS ratios significantly higher in the women. These results might be of use in establishing normal clinical ranges for serum DHA, DHAS and the DHA/DHAS ratio in women.
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