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  • Title: Left ventricular hypertrophy differences between male and female renovascular hypertensive rats.
    Author: Cabral AM, Antonio A, Moyses MR, Vasquez EC.
    Journal: Braz J Med Biol Res; 1988; 21(3):633-5. PubMed ID: 2976286.
    Abstract:
    In a previous study we demonstrated ventricular hypertrophy in male but not in female sinoaortic denervated rats. To evaluate a possible sexual influence on ventricular hypertrophy of other models for experimental hypertension, we studied two-kidney one clip and one-kidney one clip Goldblatt hypertension. The results showed left ventricular hypertrophy in male but not in female two-kidney one clip groups, despite the same arterial hypertension level in both groups. In the one-kidney one clip groups, left ventricular hypertrophy was greater in male than in female rats. The results indicate a sexual influence in ventricular hypertrophy when the arterial renovascular hypertension level is moderate.
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