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  • Title: Study of the Mozart effect in children with epileptic electroencephalograms.
    Author: Grylls E, Kinsky M, Baggott A, Wabnitz C, McLellan A.
    Journal: Seizure; 2018 Jul; 59():77-81. PubMed ID: 29763803.
    Abstract:
    PURPOSE: To establish if listening to Mozart's Sonata for two pianos in D major (K448) has an anti-epileptic effect on the EEGs (electroencephalograms) of children. METHODS: Forty five children (2-18 years; mean 7 years 10 months) who had epileptiform activity on EEG were recruited from those attending for scheduled EEG investigations. Mozart's Sonata for two pianos in D major (K448) and an age-appropriate control music were played during the EEG. There were five consecutive states during the record, each lasting 5 min; before Mozart music (baseline), during Mozart music, after Mozart music/before control music, during control music and after control music. Epileptic discharges were counted manually and the mean frequency of epileptic discharges calculated in each state. RESULTS: A significant reduction (p < 0.0005) in the frequency of epileptic discharges was found during listening to the Mozart music compared to the baseline. No evidence of a difference in mean epileptic discharges was found between the baseline and the other three states or between listening to the Mozart music and control music. CONCLUSION: This study confirms an anti-epileptic effect of Mozart music on the EEG in children, which is not present with control music. The role of 'Mozart therapy' as a treatment for drug-resistant epilepsy warrants further investigation.
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