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  • Title: Effect of exhaustive exercise on liver mitochondrial function in the rat.
    Author: Bielecki JW, Pawlicka E, Górski J.
    Journal: Acta Physiol Pol; 1988; 39(5-6):421-6. PubMed ID: 2978492.
    Abstract:
    The oxidative and phosphorylative function of rat liver mitochondria after exhaustive exercise was investigated. The stimulation of state 4 respiration (without ADP) with NADH and FADH2 dependent substrates was demonstrated. The reduction in RCR ratio (the rate of oxidation in state 3/the rate of oxidation in state 4) and enhanced activity of oligomycin sensitive ATP-ase was also found. The results suggest an inhibition of liver mitochondrial phosphorylative activity in rats exercised till exhaustion.
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