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  • Title: [The influence on the function of parathyroid after different thyroid cancer radical operation].
    Author: Chen Z, Dong HH, Ye Z.
    Journal: Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2016 Aug 05; 30(15):1232-1235. PubMed ID: 29798337.
    Abstract:
    Objective:The aim of this study is to detect the changes of parathyroid hormone and serum calcium levels before and after operation,and evaluate the effect and treatment of parathyroid function after total thyroidectomy.Method:One hundred and seventy-two cases of initial total thyroidectomy were analysed retrospectively,who were divided into simple total thyroidectomy group(A),total thyroidectomy with unilateral central lymph node dissection group(B),and total thyroidectomy with lateral central lymph node dissection group(C).We analyse the preoperative and postoperative serum calcium and parathyroid hormone.Result:In three groups,the serum concentrations of the parathyroid hormone and calcium decreased after operation.The difference was statistically significant between in B group and C group(P<0.05);The hypoparathyroidism had statistical significance between A group and C group(P<0.05).Conclusion:The possibility of hypoparathyroidism and hypocalcemia was increasing with the expansion of the range of operation.Therefore,retain vital recognition of parathyroid gland was very important in the resection of thyroid cancer especially central lymph node dissection.We should reduce the incidence of permanent hypoparathyroidism as far as possible.
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