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  • Title: Antiviral Triketone-Phloroglucinol-Monoterpene Adducts from Callistemon rigidus.
    Author: Cao JQ, Wu Y, Zhong YL, Li NP, Chen M, Li MM, Ye WC, Wang L.
    Journal: Chem Biodivers; 2018 Jul; 15(7):e1800172. PubMed ID: 29806969.
    Abstract:
    Callistrilones F - K (1 - 6), six new triketone-phloroglucinol-monoterpene hybrids were isolated from the twigs and leaves of Callistemon rigidus. Their structures with absolute configurations were established by a combination analysis of NMR spectra, X-ray diffraction, and electronic circular dichroism (ECD) calculations. Compounds 3 and 4 exhibited moderate inhibitory activities against herpes simplex virus (HSV-1) with IC50 values of 10.00 ± 2.50 and 12.50 ± 1.30 μm, respectively.
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