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  • Title: The effect of rhodopsin phosphorylation on the light-dependent activation of phosphodiesterase from bovine rod outer segments.
    Author: Arshavsky VY, Dizhoor AM, Shestakova IK, Philippov P.
    Journal: FEBS Lett; 1985 Feb 25; 181(2):264-6. PubMed ID: 2982661.
    Abstract:
    ATP quenches light-dependent phosphodiesterase (PDE) activation in rod outer segments presumably due to rhodopsin phosphorylation. Here we compared the efficiency of phosphorylated and non-phosphorylated rhodopsins as PDE activators in a reconstituted cell-free system. It is shown that the ability of phosphorylated membranes to activate this enzyme is suppressed compared with non-phosphorylated ones.
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