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  • Title: [Experimental and clinical determination of renal size after intravenous and intra-arterial administration of ionic and non-ionic contrast media].
    Author: Helzel MV, Wolf GK, Prager P.
    Journal: Rofo; 1985 Mar; 142(3):333-7. PubMed ID: 2984739.
    Abstract:
    A quantitative comparison of changes in renal size after the intravenous injection of contrast media showed no difference between ionic and non-ionic contrast medium. Contrast media of similar osmolarity (Metrizamide and Ioxaglate with 470 and 490 mosn/kg H2O) did show significant variations. Evidently properties of the contrast medium, other that their osmotic behaviour, are of significance (chemical structure, viscosity, iodine content, specific toxicity, and the effect on the permeability of biological membranes, calcium-binding activity, effect on coagulation). Changes in renal size could be reproduced by repeating the contrast injection at 24 to 48 hours.
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