These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Preferential inhibition of plasmid replication in vivo by altered DNA gyrase activity in Escherichia coli.
    Author: Uhlin BE, Nordström K.
    Journal: J Bacteriol; 1985 May; 162(2):855-7. PubMed ID: 2985550.
    Abstract:
    The thermosensitive growth phenotype exerted by runaway-mutant plasmids was suppressed by sublethal doses of the DNA gyrase inhibitors novobiocin or nalidixic acid, although the latter drug was less efficient. A novobiocin-resistant gyrB mutant Escherichia coli strain prevented expression of the runaway phenotype at 37 to 42 degrees C in the absence of any drug.
    [Abstract] [Full Text] [Related] [New Search]