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  • Title: Fluoride Penetration and Clearance Are Higher in Exopolysaccharide-Containing Bacterial Pellets.
    Author: Spinola MS, Nóbrega DF, Del Bel Cury AA, Ricomini Filho AP, Cury JA, Tenuta LMA.
    Journal: Caries Res; 2019; 53(1):16-23. PubMed ID: 29874649.
    Abstract:
    Extracellular polysaccharides (EPS) could increase the penetration of fluoride through dental biofilm, reducing its cariogenicity. We measured the concentration of fluoride in EPS-containing (EPS+) or not-containing (EPS-) Streptococcus mutans bacterial pellets resembling test biofilms, before and up to 60 min after a 0.05% NaF rinse in situ. Fluoride penetration and clearance were higher in EPS+ bacterial pellets. The data suggest that EPS enhances fluoride penetration, but also accelerates fluoride clearance from dental biofilms.
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