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  • Title: Prevalence of serological hepatitis A and B markers in a rural area of northern Zaire.
    Author: Werner GT, Frösner GG, Fresenius K.
    Journal: Am J Trop Med Hyg; 1985 May; 34(3):620-4. PubMed ID: 2988353.
    Abstract:
    In a seroepidemiological study of the population of a rural area in northern Zaire, markers of hepatitis A and B were determined. Examinations of serum specimens (n = 142) showed that hepatitis A is acquired early in childhood; virtually all persons beyond 20 years of age are immune. Capillary blood dried on filter discs (n = 352) gave accurate results only in childhood; in older individuals a high percentage of positive results was missed (approximately 20%), presumably due to lower anti-HAV titers in older persons. The dried-blood method showed similar limitations regarding the detection of hepatitis B markers. In the 5-7 year age group there was already a high prevalence of anti-HBc (59%) as determined by the dried blood method. In the 10-19 year age group the prevalence was 94% as determined by examination of serum specimens. In all age groups the percentage of HBsAg positive persons was 20.7%, as demonstrated in capillary blood specimens and 31.7% in serum specimens.
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