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  • Title: Incidence of Macular Holes in the Fellow Eye without Vitreomacular Detachment at Baseline.
    Author: Philippakis E, Astroz P, Tadayoni R, Gaudric A.
    Journal: Ophthalmologica; 2018; 240(3):135-142. PubMed ID: 29895011.
    Abstract:
    PURPOSE: To determine the rate of macular holes (MH) occurring in the fellow eyes of eyes with MH depending on the vitreomacular interface at baseline. METHODS: This was a retrospective study of patients operated on for idiopathic MH, with persistent vitreofoveal attachment in the fellow eye assessed by spectral-domain optical coherence tomography (SD-OCT). Follow-up lasted 6 months or more, and the main outcome was the occurrence of an MH. RESULTS: The 77 fellow eyes included had a mean follow-up of 34.11 ± 22.3 months (6-78.4). At baseline, 31 eyes had vitreomacular traction (VMT), 35 vitreomacular adhesion, and 11 no posterior vitreous detachment. MH occurred in 19.5% of the cases (15/77). The rate of MH was significantly higher among the eyes with VMT than among the eyes without VMT at baseline (35.5 vs. 8.7%; p = 0.009). CONCLUSION: One-third of eyes with VMT at baseline identified by SD-OCT will develop an MH in the following 5 years.
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