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  • Title: Flow Cytometry to Evaluate Potential Developmental Toxicants in the Embryonic Stem Cell.
    Author: Lara VM, Santos Roballo KC, Gotardo AT, Ambrósio CE.
    Journal: Methods Mol Biol; 2018; 1797():165-175. PubMed ID: 29896691.
    Abstract:
    Embryonic stem cells (ESC) are widely used due to their unlimited capacity of differentiation into different cell lineages, which makes ESC a viable choice as a toxicology test model. Toxicological analysis using embryonic stem cells (ESC) has become an important tool in toxicology procedures. Regarding toxicological analysis methods, flow cytometry (FC) is one technique designed to detect and evaluate cells in suspension, for example, ESC suspension, thus making possible to study different biological, physical, and/or chemical characteristics of cells. Thus, FC can be very useful for cell toxicology and tumorigenic analyses.
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