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  • Title: Parthenogenetic activation decreases the polyphosphoinositide content of frog eggs.
    Author: Le Peuch Cj, Picard A, Dorée M.
    Journal: FEBS Lett; 1985 Jul 22; 187(1):61-4. PubMed ID: 2991011.
    Abstract:
    Polyphosphoinositides were quantified in metaphase II-arrested eggs of the amphibian Xenopus laevis and 8-10 min later in eggs activated by pricking. The content of phosphatidylinositol 4,5-biphosphate (PIP2) was remarkably high in metaphase II-arrested eggs with respect to that of phosphatidylinositol 4-phosphate (PIP). It was found to drop dramatically at activation. In contrast PIP content did not change significantly.
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