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  • Title: The second human calcitonin/CGRP gene is located on chromosome 11.
    Author: Höppener JW, Steenbergh PH, Zandberg J, Geurts van Kessel AH, Baylin SB, Nelkin BD, Jansz HS, Lips CJ.
    Journal: Hum Genet; 1985; 70(3):259-63. PubMed ID: 2991116.
    Abstract:
    A second human calcitonin/calcitonin gene related peptide (hCT/CGRP) gene has been identified. This second hCT/CGRP gene has been shown to contain sequences highly homologous to exons 3, 5 (CGRP-encoding), and 6 of the first hCT/CGRP gene, but sequences closely related to exon 4 (CT-encoding) could not be demonstrated. Southern blot hybridization analysis of DNA from human-rodent somatic cell hybrids showed that the second hCT/CGRP gene is located in the q12-pter region of chromosome 11. The first hCT/CGRP gene has previously been assigned to the p13-p15 region of chromosome 11.
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