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  • Title: [Cyclic nucleotide levels in the regenerating liver of rats following irradiation and protection by serotonin].
    Author: Aslamova LI, Blium IaB, Tsudzevich BA, Kucherenko NE.
    Journal: Radiobiologiia; 1985; 25(3):324-7. PubMed ID: 2991974.
    Abstract:
    Changes in cAMP and cGMP levels after X-irradiation and radioprotective treatment with serotonin were studied using a model of impulse inhibition and repair of transcription, translation and replication by cycloheximide in rat hepatocytes in vivo. Irradiation was shown to inhibit the cyclic nucleotide synthesis. Serotonin increased the contents of cAMP and cGMP maintaining their elevated level after X-irradiation.
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