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  • Title: Isolation of a lymphadenopathy-associated virus from a patient with the acquired immune deficiency syndrome.
    Author: Becker ML, Spracklen FH, Becker WB.
    Journal: S Afr Med J; 1985 Aug 03; 68(3):144-7. PubMed ID: 2992103.
    Abstract:
    A virus similar to the lymphadenopathy-associated virus or human T-lymphotropic virus type III, which has been described in association with the acquired immune deficiency syndrome (AIDS) by several laboratories elsewhere in the world, was isolated from a Cape Town patient with lymphadenopathy and acquired immune deficiency. This virus has the characteristic morphogenesis and ultrastructure and its genome encodes the virus-specific p24 protein. It is T-lymphotropic and produces the characteristic cytopathic effect. It can be serially propagated in a human lymphocyte line of the T4+ phenotype. This isolate is being used in diagnostic immunofluorescence assays for virus-specific antibodies.
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